Particle Size Reduction

  • The role of particle size on function and flavor is important for food, chemical and pharma
  • Particle size reduction – milling options to reduce size via different mechanism for feedstocks ranging from high and low fat powders to high and low moisture grains, seeds, carbohydrates, protein, fibers and nutmeats. Mechanisms for particulate breakage includes shear, compression, impact.

Particle size reduction is a process that involves breaking down materials into smaller particles. There are several technologies used for particle size reduction, including mechanical milling, jet milling, and ball milling.

Mechanical milling is a process that involves the use of a mechanical force to break down particles. This can be achieved using a variety of machines, including hammer mills, attrition mills, and roller mills. Mechanical milling is often used in the food industry to grind up grains, spices, and other ingredients into smaller particles.

Ball milling is a process that involves the use of balls or other milling media to break down particles. In ball milling, particles are placed in a container along with the milling media and rotated at high speeds. As the container rotates, the milling media collide with the particles, breaking them down into smaller particles. Ball milling is often used in the manufacturing of pigments and other fine chemicals.

Regardless of the technology used, particle size reduction is an important process in many industries. Smaller particle sizes can improve the properties of materials, such as increasing their surface area, improving their reactivity, and enhancing their solubility.

Drying

Forced convection and radiant ovens (Binder, Across) with drying curve capability, RotoVap, vacuum oven, freeze drying (Buchi and SP Scientific), spray drying and more.

Storage Conditions

Mixing

Mixing is likely the most common unit operation for manufacturing , and likely the least understood. Many legacy processes exist that were designed through empirical and trial and error approaches. The rationale and good engineering principles employed as a fit for purpose operation is often lost or not understood. These then become the ‘black box’ step which leads to issues as new ingredient or recipes are introduced or operational desire to improve capacity.

Mechanical mixing is a technology used to mix materials using mechanical forces such as stirring, shaking, or tumbling. It is a widely used method in many industries, including food, pharmaceuticals, and chemicals. The process involves using equipment such as mixers, blenders, or agitators to combine substances and create a homogeneous mixture.

There are different types of mechanical mixers, each with its unique design and mixing principle. Some of the most common types include:

  1. Ribbon mixers: These mixers have a ribbon-shaped agitator that rotates in a U-shaped trough. The ribbon agitator moves the materials in one direction, then the other, creating a consistent mixing motion.
  2. Paddle mixers: These mixers use paddles or blades that rotate around a central shaft to mix materials. Paddle mixers are commonly used in the food industry for mixing dry ingredients, such as flour or sugar.
  3. Planetary mixers: These mixers have a planetary motion, where the agitator rotates on its own axis while orbiting around the central mixing bowl. Planetary mixers are commonly used in the cosmetics and pharmaceutical industries.
  4. Sigma blade (aka Banbury, Double Z blade): these mixers typically have two sigma shaped geometry blades overlapping or independent rotating at nominallly 60-100 rpms. These mixers can be jacketted and provide high torque capable of handling materials that flow, but have very high viscosities.

Plough (aka ploughshare, paddle) these mixers are single shaft with plough agitators rotating up to nominally 300 rpm. These mixers can be jacketted and provide high torque capable of handling powders, pastes, liquid and very high viscosity fluids. Machines can also serve to coat, agglomerate and dry powders w/wo vacuum making it a versatile unit operation. Capacity can range from 25-80% of rated volume.

High shear mixers: These mixers use a high-speed rotor or impeller to create shear forces that reduce droplet sizes for emulsions and solids containing suspensions. They can also serve to provide intensive energy input for mixing applications. High shear mixers are commonly used in the chemical and pharmaceutical industries for mixing and dispersing particles.

In mechanical mixing, the type of mixer and the mixing speed are crucial in achieving the desired mixing outcome. Proper mixing ensures that all ingredients are evenly distributed and combined to create a uniform product.

Analytical Characterization